Initial Experience with ZAP-X Radiosurgery for Recurrent Tumors
Author Information
Author(s): Muacevic Alexander, Adler John R, Horiba Ayako, Hayashi Motohiro, Maruyama Takashi, Nomura Ryutaro, Kim Phyo, Kawamata Takakazu
Primary Institution: Tokyo Women's Medical University
Hypothesis
Can the ZAP-X radiosurgery system effectively treat intracranial lesions that have recurred after Gamma Knife treatment?
Conclusion
ZAP-X demonstrated strong anti-tumor efficacy and tolerability in patients with recurrent disease following Gamma Knife treatment.
Supporting Evidence
- The six-month progression control rate was 100%.
- Two patients showed partial responses and four showed stable disease.
- Adverse events were limited to imaging changes in one patient.
Takeaway
Doctors used a new machine called ZAP-X to treat patients with brain tumors that came back after previous treatment, and it worked really well.
Methodology
Patients with recurrent intracranial tumors treated with ZAP-X were evaluated for progression control and adverse events.
Limitations
The study is limited by a short observation period after treatment.
Participant Demographics
The mean age of participants was 59.8 years, with five out of six being male.
Statistical Information
P-Value
0.038
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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