A DFT Study on Deactivation of Triplet Excited State Riboflavin by Polyphenols
2008

How Polyphenols Deactivate Riboflavin's Excited State

publication Evidence: moderate

Author Information

Author(s): Ji Hong-Fang Shen Liang

Primary Institution: Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Center for Advanced Study, Shandong University of Technology

Hypothesis

The study investigates how polyphenols like rutin and catechin deactivate the triplet excited state of riboflavin.

Conclusion

The H-atom transfer pathway is the most thermodynamically favorable mechanism for deactivating the triplet excited state of riboflavin by polyphenols.

Supporting Evidence

  • The study found that the H-atom transfer pathway is more feasible than direct energy or electron transfer pathways for riboflavin deactivation.
  • Rutin and catechin were identified as effective antioxidants that can quench the triplet excited state of riboflavin.

Takeaway

This study shows that certain plant compounds can help stop riboflavin from causing damage when it gets excited by light.

Methodology

Density functional theory calculations were used to study the deactivation mechanisms of triplet excited state riboflavin by polyphenols.

Digital Object Identifier (DOI)

10.3390/ijms9101908

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