Endothelial Function and Urine Albumin Levels in Mexican-Americans and Non-Hispanic Whites
Author Information
Author(s): Gardin Julius M, Allebban Zuhair, Wong Nathan D, Sklar Sharon K, Bess Renee L, Spence M Anne, Pershadsingh Harrihar A
Primary Institution: Division of Cardiology, Department of Medicine, St. John Hospital & Medical Center, Detroit, MI, USA
Hypothesis
There are significant differences in FMD between Mexican-Americans and non-Hispanic whites, and these differences relate to ethnic differences in the levels of traditional CHD risk factors.
Conclusion
The study found that Mexican-Americans demonstrated higher flow-mediated dilatation compared to non-Hispanic whites, despite having higher BMI and triglycerides.
Supporting Evidence
- Mexican-Americans exhibited higher flow-mediated dilatation than non-Hispanic whites.
- Urinary albumin levels were lower in Mexican-Americans with higher flow-mediated dilatation.
- The study suggests ethnic differences in subclinical cardiovascular disease measures.
Takeaway
This study looked at how healthy Mexican-Americans and non-Hispanic whites differ in their blood vessel function and protein levels in urine, finding that Mexican-Americans had better blood vessel function.
Methodology
The study involved 105 Mexican-American and 100 non-Hispanic white adults, using ultrasound to measure flow-mediated dilatation and conducting blood and urine tests.
Limitations
The sample size was relatively small, and a substantial proportion of the variability of brachial FMD remains unexplained by standard CVD risk factors.
Participant Demographics
105 Mexican-Americans (42 men, 63 women, age 46 ± 14 yrs) and 100 non-Hispanic whites (59 men, 41 women, age 50 ± 11 yrs).
Statistical Information
P-Value
p < 0.04
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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