Antihypertensive Effect of Perla and Esmeralda Barley (Hordeum vulgare L.) Sprouts in an Induction Model with L-NAME In Vivo
2024

Effects of Barley Sprouts on Blood Pressure

Sample size: 56 publication 10 minutes Evidence: moderate

Author Information

Author(s): García-Castro Abigail, Román-Gutiérrez Alma D., Guzmán-Ortiz Fabiola A., Cariño-Cortés Raquel

Primary Institution: Autonomous University of the State of Hidalgo

Hypothesis

Can extracts from Perla and Esmeralda barley sprouts effectively regulate blood pressure in hypertensive rats?

Conclusion

Barley extracts significantly reduced blood pressure and improved kidney function in hypertensive rats.

Supporting Evidence

  • Esmeralda barley extract showed 83% inhibition of ACE activity in vitro.
  • Combined administration of barley extract and captopril reduced blood pressure by 22%.
  • Barley extracts improved renal function by reducing creatinine and urea levels.
  • Plasma NO concentrations increased by 66% with barley extract treatment.

Takeaway

Barley sprouts can help lower blood pressure and make your kidneys healthier.

Methodology

The study used male Wistar rats, dividing them into groups to assess the effects of barley extracts on blood pressure and kidney function over 35 days.

Potential Biases

Potential bias due to the use of a single animal model and the specific barley varieties tested.

Limitations

The study primarily focused on animal models, and further research is needed to confirm findings in humans.

Participant Demographics

Male Wistar rats aged 8-10 weeks, weighing 200-220 g.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/metabo14120678

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