Antibiotic Resistance Patterns in Urinary Tract Infections in Aligarh, India
Author Information
Author(s): Akram Mohammed, Shahid Mohammed, Khan Asad U
Primary Institution: Interdisciplinary Biotechnology Unit, Aligarh Muslim University
Hypothesis
What are the distribution and antibiotic susceptibility patterns of bacterial strains isolated from patients with community-acquired urinary tract infections at JN Medical College and Hospital in Aligarh, India?
Conclusion
E. coli was the predominant bacterial pathogen of community-acquired UTIs in Aligarh, India, with increasing resistance to Co-trimoxazole and production of extended spectrum β-lactamase among UTI pathogens.
Supporting Evidence
- E. coli accounted for 61% of the isolated pathogens.
- 42% of isolates were found to produce ESBL.
- Resistance to ampicillin and co-trimoxazole was high among the isolates.
Takeaway
This study found that many people in Aligarh, India, have urinary infections caused by bacteria that are hard to treat because they resist common antibiotics.
Methodology
Urinary isolates from symptomatic UTI cases were identified and tested for antibiotic susceptibility using the Kirby Bauer's disc diffusion method.
Potential Biases
Potential bias due to the study being conducted in a single location and the retrospective nature of the data collection.
Limitations
The study was retrospective and only included patients from a single hospital.
Participant Demographics
Patients ranged from newborns to 80 years old, with a higher prevalence in women (66.66%).
Statistical Information
P-Value
0.000
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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