Inflammatory myopathy and severe rhabdomyolysis induced by leuprolide acetate therapy for prostate cancer: a case report
2011
Severe Muscle Weakness and Kidney Failure from Prostate Cancer Treatment
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Michael Bergner, Martin Rohacek, Paul Erne
Primary Institution: Luzerner Kantonsspital, University Hospital Bern
Conclusion
Leuprolide acetate therapy can lead to severe side effects such as inflammatory myopathy, rhabdomyolysis, and renal failure.
Supporting Evidence
- The patient experienced severe muscle weakness and kidney failure after receiving leuprolide acetate.
- Steroid therapy led to remission of symptoms within six weeks.
- This case highlights the potential severe side effects of leuprolide acetate therapy.
Takeaway
A man taking a medicine for prostate cancer got very weak and had kidney problems because of the medicine, but he got better after stopping it and taking steroids.
Methodology
The patient was treated with leuprolide acetate, and a muscle biopsy was performed to diagnose the condition.
Limitations
This is a single case report, limiting the generalizability of the findings.
Participant Demographics
64-year-old Swiss Caucasian man.
Digital Object Identifier (DOI)
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