A Retrospective Study Reviewing Timing to Onset of Habitual Psychogenic Non-Epileptic Seizures in a Home Video Telemetry Cohort
2024

Timing of Psychogenic Non-Epileptic Seizures in Home Video Telemetry

Sample size: 37 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jade Cooper, Helen Chester, Arianna Fozzato, Elisaveta Sokolov

Primary Institution: Guy’s and St Thomas’ NHS Foundation Trust

Hypothesis

Patients presenting with PNES would have their typical event in less than 24 hours.

Conclusion

Patients with PNES typically have their first habitual event within seven hours of starting home video telemetry.

Supporting Evidence

  • The mean time to first habitual PNES onset was seven hours.
  • Patients with abnormal MRI findings had their events earlier than those with normal findings.
  • Men presented significantly earlier with their habitual PNES event than women.

Takeaway

This study found that people with certain types of seizures called PNES usually have their first seizure within seven hours of starting a video recording at home.

Methodology

A retrospective analysis of a cohort of patients who underwent home video telemetry for suspected PNES.

Potential Biases

Self-reporting may introduce bias as patients may not accurately describe their events.

Limitations

The study relied on self-reported data without witness validation, and some patients were excluded due to technical issues.

Participant Demographics

The majority of participants were female (84%) with a mean age of 38.

Statistical Information

P-Value

0.04 for gender association, 0.02 for MRI findings association

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/brainsci14121187

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