Efficient Explainable Models for Alzheimer’s Disease Classification with Feature Selection and Data Balancing Approach Using Ensemble Learning
2024

Efficient Explainable Models for Alzheimer’s Disease Classification

Sample size: 2149 publication 10 minutes Evidence: high

Author Information

Author(s): Dubey Yogita, Bhongade Aditya, Palsodkar Prachi, Fulzele Punit

Primary Institution: Yeshwantrao Chavan College of Engineering, Nagpur, India

Hypothesis

This paper aims to propose a computationally efficient, reliable, and transparent machine learning-based framework for the classification of Alzheimer’s disease patients.

Conclusion

The proposed approach achieved the best accuracy of 95%, demonstrating its effectiveness and potential for reliable early diagnosis of Alzheimer’s disease.

Supporting Evidence

  • The proposed framework integrates explainable AI tools to enhance model transparency.
  • Random sampling was used to mitigate data imbalance.
  • Feature analysis identified the most impactful clinical features for Alzheimer's diagnosis.
  • Ensemble learning algorithms were employed to improve classification accuracy.

Takeaway

This study created a smart computer program to help doctors figure out if someone has Alzheimer's disease by looking at their health data.

Methodology

The study used boosting algorithms, random sampling for data balancing, and feature selection techniques to improve model performance.

Potential Biases

The model may be biased if the dataset is not representative of the broader population.

Limitations

The study may not generalize well across different populations due to the specific dataset used.

Participant Demographics

Patients aged 60 to 90, with a majority being female.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/diagnostics14242770

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