Invasive Aspergillosis and Small Bowel Infarction in a Breast Cancer Patient
Author Information
Author(s): Amit Chaudhary, Vinod Jain, Rama S. Dwivedi, Samir Misra
Primary Institution: King George Medical University, Lucknow, India
Hypothesis
Can invasive gastrointestinal aspergillosis be diagnosed in neutropenic patients presenting with acute abdominal symptoms?
Conclusion
Invasive gastrointestinal aspergillosis should be considered in neutropenic patients with acute abdominal symptoms.
Supporting Evidence
- The patient developed severe neutropenia after chemotherapy.
- Histopathology revealed bowel wall necrosis and vascular invasion by Aspergillus.
- The patient was successfully treated with intravenous Amphotericin-B.
Takeaway
A woman with breast cancer got a serious infection in her intestines from a fungus while getting chemotherapy, but she got better after treatment.
Methodology
The patient underwent exploratory laparotomy, and the diagnosis was confirmed through bronchoalveolar lavage and a positive galactomannan test.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A 45-year-old female with Stage IV breast cancer.
Digital Object Identifier (DOI)
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