Study of Pulmonary Zygomycosis Cases
Author Information
Author(s): Challa Sundaram Uppin, Shantveer G. Uppin, Megha S. Paul, Roshni T. Prayaga, Aruna K. Rao, Manmadha T.
Primary Institution: Nizam’s Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
Hypothesis
What are the clinical and pathological features of pulmonary zygomycosis in patients diagnosed in India?
Conclusion
Diabetes mellitus is the most common predisposing factor for pulmonary zygomycosis and carries high mortality.
Supporting Evidence
- Seven patients were diagnosed with pulmonary zygomycosis during the study period.
- Six of the patients had diabetes mellitus as a predisposing factor.
- Fever and cough were the most common symptoms among the patients.
- Histological examination revealed necrotizing inflammation and fungal hyphae.
- Five patients succumbed to the disease, highlighting the high mortality rate.
Takeaway
This study looked at seven patients with a rare lung infection caused by a fungus, mostly affecting people with diabetes, and many of them did not survive.
Methodology
The study included all cases of pulmonary zygomycosis diagnosed on histopathology from 1995 to 2008, noting clinical, radiological, and treatment outcomes.
Limitations
The study is limited by the small sample size and the retrospective nature of data collection.
Participant Demographics
Six males and one female, aged 40-60 years, with most having diabetes mellitus.
Digital Object Identifier (DOI)
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