Effect of Embelia ribes on Cholesterol and Blood Sugar in Diabetic Rats
Author Information
Author(s): Uma Bhandari, Raman Kanojia, K. K. Pillai
Primary Institution: Hamdard University
Hypothesis
The ethanolic extract of Embelia ribes will lower blood glucose and improve lipid profiles in diabetic rats.
Conclusion
The ethanolic extract of Embelia ribes significantly reduced blood glucose, total cholesterol, and triglycerides while increasing HDL-cholesterol in diabetic rats.
Supporting Evidence
- Rats treated with E. ribes showed a significant decrease in blood glucose levels.
- The extract reduced serum total cholesterol and triglycerides.
- HDL-cholesterol levels increased in rats treated with E. ribes.
- The results were comparable to the standard drug gliclazide.
- Oxidative stress was reduced in the liver and pancreas of treated rats.
Takeaway
This study shows that a plant called Embelia ribes can help lower bad fats and sugar levels in sick rats.
Methodology
Diabetic rats were treated with ethanolic extract of E. ribes for 20 days, and various biochemical parameters were measured.
Limitations
The study was conducted only on rats, and further research is needed to confirm the effects in humans.
Participant Demographics
Wistar rats of either sex, weighing 150 to 200 g.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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