Optimal and continuous anaemia control in a cohort of dialysis patients in Switzerland
2008

Long-term Anaemia Control in Dialysis Patients in Switzerland

Sample size: 350 publication 10 minutes Evidence: moderate

Author Information

Author(s): Mathieu Claudine M, Teta Daniel, Lötscher Nathalie, Golshayan Dela, Gabutti Luca, Kiss Denes, Martin Pierre-Yves, Burnier Michel

Primary Institution: University Hospital CHUV, Department of Nephrology, Lausanne, Switzerland

Hypothesis

Can continuous long-term anaemia control be achieved in dialysis patients in Switzerland?

Conclusion

This study shows that Swiss dialysis centres achieved remarkable and continuous control of anaemia through careful management and EPO dosing.

Supporting Evidence

  • 85% of patients achieved mean Hb ≥ 11 g/dL.
  • Mean Hb was stable at 11.9 ± 1.0 g/dL over the year.
  • One year survival was significantly higher in patients with Hb ≥ 11 g/dL.

Takeaway

Doctors in Switzerland helped kidney patients keep their blood levels healthy over a year by giving them medicine and checking them regularly.

Methodology

A prospective multi-centre observational study with monthly assessments over one year.

Potential Biases

Selection bias cannot be formally excluded as there was no random selection.

Limitations

The study includes a relatively small number of patients and did not account for several factors influencing Hb levels.

Participant Demographics

{"mean_age":63.9,"gender_distribution":{"female":41.4,"male":58.5},"dialysis_type":{"haemodialysis":94.9,"peritoneal_dialysis":5.1}}

Statistical Information

P-Value

0.006

Confidence Interval

95% CI: 127–146 IU/kg/week

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2369-9-16

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication