Flavonoid Analysis and Antimicrobial Activity of Phaleria macrocarpa Fruit
Author Information
Author(s): Hendra Rudi, Ahmad Syahida, Sukari Aspollah, Shukor M. Yunus, Oskoueian Ehsan
Primary Institution: Universiti Putra Malaysia
Hypothesis
The study investigates the biological activities of Phaleria macrocarpa fruit by characterizing its flavonoids and assessing its antimicrobial activity against pathogenic bacteria and fungi.
Conclusion
Phaleria macrocarpa fruit contains flavonoids that contribute to its antimicrobial properties, making it a potential natural source for antimicrobial agents.
Supporting Evidence
- Kaempferol, myricetin, naringin, and rutin were identified as the major flavonoids in the pericarp of P. macrocarpa fruit.
- The antibacterial activity of P. macrocarpa fruit extracts showed weak to moderate inhibition against various pathogenic bacteria.
- The seed extract exhibited antifungal activity against Aspergillus niger.
Takeaway
This study found that a fruit called Phaleria macrocarpa has special compounds that can help fight germs, which might be useful for medicine.
Methodology
Flavonoid compounds were analyzed using Reversed-Phase High Performance Liquid Chromatography (RP-HPLC) and antimicrobial activity was assessed using disc diffusion and agar well diffusion methods.
Limitations
The study primarily focused on the antimicrobial activity of the fruit extracts without exploring other potential biological activities.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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