Recall of intestinal helminthiasis by HIV-infected South Africans and avoidance of possible misinterpretation of egg excretion in worm/HIV co-infection analyses
2006

Recall of Intestinal Worms in HIV-Infected South Africans

Sample size: 235 publication 10 minutes Evidence: moderate

Author Information

Author(s): Vera J. Adams, Miles B. Markus, Zilungile L. Kwitshana, Muhammad A. Dhansay, Lize van der Merwe, Gerhard Walzl, John E. Fincham

Primary Institution: Medical Research Council of South Africa

Hypothesis

When Ascaris is hyperendemic, analysis of possible consequences of co-infection by HIV cannot be based primarily on excretion vs non-excretion of eggs.

Conclusion

There was a long-term history of ascariasis in both HIV-positive and HIV-negative groups, indicating significant co-infection implications.

Supporting Evidence

  • Over 70% of participants recalled having passed worms as children or adults.
  • HIV-positive participants had more recall of deworming treatments.
  • More than 90% of participants moved to the city from rural areas.

Takeaway

Many people in South Africa remember having worms when they were kids, and those with HIV seem to have had more worm infections.

Methodology

Participants were asked about their history of worm infections and deworming treatments through a questionnaire.

Potential Biases

Participants may have been influenced by stigma associated with HIV, affecting their willingness to disclose information.

Limitations

The study relied on participants' recall of past infections, which may not be entirely accurate.

Participant Demographics

The study included 170 HIV-positive and 65 HIV-negative adults, predominantly women.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI 20.7 – 29.1

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2334-6-88

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