A Pressing Emergency in Oncology: A Case Series of Patients With Posterior Reversible Encephalopathy Syndrome
2024

A Case Series of Patients With Posterior Reversible Encephalopathy Syndrome

Sample size: 7 publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Narasimhan Vikram L, Kumar P Pavan

Primary Institution: Vydehi Institute of Medical Sciences and Research Centre

Hypothesis

Can posterior reversible encephalopathy syndrome (PRES) occur in normotensive cancer patients?

Conclusion

PRES is a neurological emergency that can occur in normotensive patients with cancer, and symptoms are often reversible.

Supporting Evidence

  • All patients achieved nearly full neurological recovery by 28 days.
  • The 90-day all-cause mortality rate was 14%.
  • No patient exhibited significantly elevated blood pressure during their inpatient stay.

Takeaway

This study looked at seven cancer patients who had a brain condition called PRES, which can make them feel very sick, but they mostly got better.

Methodology

This was a retrospective case series of seven patients diagnosed with PRES, focusing on clinical characteristics and outcomes.

Limitations

The study had a small sample size and lacked a control group and statistical analysis.

Participant Demographics

The cohort included four females (57%) and three males (43%) with a median age of 48 years.

Digital Object Identifier (DOI)

10.7759/cureus.75028

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