Risk factors for oesophageal, lung, oral and laryngeal cancers in black South Africans
2002

Risk Factors for Oesophageal, Lung, Oral, and Laryngeal Cancers in Black South Africans

Sample size: 2900 publication 10 minutes Evidence: high

Author Information

Author(s): Pacella-Norman R, Urban M I, Sitas F, Carrara H, Sur R, Hale M, Ruff P, Patel M, Newton R, Bull D, Beral V

Primary Institution: MRC/CANSA/NHLS/WITS Cancer Epidemiology Research Group

Hypothesis

What are the risk factors for oesophageal, lung, oral, and laryngeal cancers in black South Africans?

Conclusion

Tobacco smoking is the major risk factor for oesophageal, lung, oral, and laryngeal cancers in black South Africans.

Supporting Evidence

  • Tobacco smoking was found to be the major risk factor for all cancers studied.
  • Long-term residence in the Transkei region is a significant risk factor for oesophageal cancer.
  • Frequent alcohol consumption increases the risk of oesophageal cancer, especially in smokers.

Takeaway

Smoking is really bad for you and can cause serious cancers, especially for people living in South Africa.

Methodology

Data was collected from a cancer case-control study using structured interviews with newly diagnosed cancer patients.

Potential Biases

Potential bias due to self-reported smoking and alcohol consumption.

Limitations

The study may not cover individuals with access to private medical care, which could affect smoking rates.

Participant Demographics

The study included 1586 females and 1314 males, all black South Africans.

Statistical Information

Confidence Interval

95% CI 1.5–4.5

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600338

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