Cefixime for Treating Gonorrhea in Pregnant Women
Author Information
Author(s): Joseph M. Miller, Jr.
Primary Institution: Louisiana State University Medical Center
Hypothesis
The study aimed to determine the efficacy and tolerance of a single dose of oral cefixime in treating pregnant women with gonorrhea.
Conclusion
A single 400 mg oral dose of cefixime was effective for treating gonorrhea and was well tolerated by pregnant women.
Supporting Evidence
- The cure rate for cefixime was found to be 95.2%.
- Side effects were reported in only three patients.
- Treatment was successful in 79 of 83 patients who had tests of cure.
Takeaway
This study found that giving pregnant women a single pill of cefixime can help cure gonorrhea without causing many side effects.
Methodology
A retrospective review of clinic records over a 3-year period identified patients treated with a single 400 mg dose of cefixime for gonorrhea during pregnancy.
Limitations
The study relied on patient recall for side effects and did not keep diaries.
Participant Demographics
Participants were primarily young, with a median age of 18 years, mostly African-American, and included both nulliparous and multiparous women.
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