Chlorhexidine varnishes effectively inhibit Porphyromonas gingivalis and Streptococcus mutans — an in vivo study
2010

Chlorhexidine Varnishes Reduce Harmful Oral Bacteria

Sample size: 30 publication Evidence: moderate

Author Information

Author(s): George Ashwin Mathew, Kalangi Suresh Kumar, Vasudevan Mithuna Krishnaswamy

Primary Institution: Ragas Dental College, Chennai, Tamil Nadu, India

Hypothesis

Does chlorhexidine varnish effectively reduce the counts of Streptococcus mutans and Porphyromonas gingivalis in patients undergoing orthodontic treatment?

Conclusion

Chlorhexidine varnishes can significantly reduce harmful bacteria and improve oral health without the side effects of traditional mouth rinses.

Supporting Evidence

  • Chlorhexidine varnish significantly reduced S. mutans counts at 1 month.
  • There was a significant reduction in P. gingivalis counts at both 1 and 3 months.
  • The varnish did not cause the side effects associated with mouth rinses.

Takeaway

This study shows that a special varnish can help keep your mouth healthy by reducing bad bacteria that cause cavities and gum problems.

Methodology

A split-mouth technique was used with 30 patients, applying chlorhexidine varnish to one side and a placebo to the other, measuring bacterial counts at baseline, 1 month, and 3 months.

Limitations

The effectiveness of the varnish on S. mutans decreased by the end of 3 months.

Participant Demographics

Patients undergoing orthodontic treatment.

Statistical Information

P-Value

0.026 for S. mutans at 1 month; 0.00 for gingival index at 3 months

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4103/0972-124X.75913

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