Patient adherence to tuberculosis treatment: A systematic review of qualitative research
2007

Understanding Patient Adherence to Tuberculosis Treatment

Sample size: 3213 publication Evidence: moderate

Author Information

Author(s): Munro Salla A, Lewin Simon A, Smith Helen J, Engel Mark E, Fretheim Atle, Volmink Jimmy

Primary Institution: South African Cochrane Centre, Medical Research Council of South Africa

Hypothesis

What factors influence patients' adherence to tuberculosis treatment?

Conclusion

A range of interacting factors can lead to patients deciding not to complete their course of tuberculosis treatment.

Supporting Evidence

  • Patients often stop taking their TB medication when they feel better, thinking they are cured.
  • Financial burdens and the organization of treatment significantly impact adherence.
  • Social stigma and fear of discrimination can prevent patients from seeking treatment.

Takeaway

Taking medicine for tuberculosis is hard for many people because of things like money problems, feeling better too soon, and not understanding the treatment.

Methodology

The study involved a systematic review of qualitative studies, synthesizing findings using meta-ethnography.

Potential Biases

Some studies may have biases due to poor quality reporting and lack of detailed descriptions of treatment regimens.

Limitations

The findings are limited by the quality and foci of the included studies, which were mostly conducted in developing countries.

Participant Demographics

Participants included TB patients, caregivers, and health care providers from various socioeconomic backgrounds.

Digital Object Identifier (DOI)

10.1371/journal.pmed.0040238

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