Correlation of Red Cell Distribution Width With Peripheral Blood Smear
Author Information
Author(s): Muacevic Alexander, Adler John R, Abbas Sumira, Shah Mian Mufarih, Iftikhar Mehwash
Primary Institution: Peshawar Medical College, Kuwait Teaching Hospital, Peshawar
Hypothesis
The study aims to correlate the red cell distribution width (RDW) with peripheral blood smear findings in anemic patients.
Conclusion
Microcytic hypochromic anemia was the most prevalent type on the peripheral blood smear, showing a significant correlation with red cell distribution width.
Supporting Evidence
- Statistically significant correlations were observed between red cell distribution width and most peripheral blood smear findings.
- Microcytic RBCs were found in 270 (60.0%) patients.
- Hypochromic RBCs were found in 301 (66.9%) cases.
- Anisocytosis showed significant correlations with red cell distribution width.
- The mean age of patients was 25.72 ± 23.23 years.
Takeaway
This study looked at blood samples from sick people to see how a specific measurement (RDW) relates to the shape and size of their red blood cells. It found that many had a type of anemia where the red blood cells were small and pale.
Methodology
This cross-sectional study included 450 patients aged 18 and above with confirmed or suspected anemia, and peripheral blood smear analysis was performed by two independent hematologists.
Potential Biases
Observer bias was minimized by having two independent hematologists analyze the blood smears.
Limitations
The use of a non-probability sampling technique may affect the representativeness of the sample, and the study was conducted at a single hospital, limiting generalizability.
Participant Demographics
The study included 232 women (51.6%) and 218 men (48.4%), with a mean age of 25.72 years.
Statistical Information
P-Value
<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website