Intrafraction motion of the prostate during an IMRT session: a fiducial-based 3D measurement with Cone-beam CT
2008

Prostate Motion During IMRT Treatment

Sample size: 5 publication Evidence: moderate

Author Information

Author(s): Judit Boda-Heggemann, Frederick Marc Köhler, Hansjörg Wertz, Michael Ehmann, Brigitte Hermann, Nadja Riesenacker, Beate Küpper, Frank Lohr, Frederik Wenz

Primary Institution: Department of Radiation Oncology, University Medical Center Mannheim

Hypothesis

What is the magnitude of intrafraction motion of the prostate during an IMRT session?

Conclusion

The overall displacement vector length during an IMRT session is less than 3 mm.

Supporting Evidence

  • The median overall displacement vector length of 125I-seeds was 3 mm.
  • Median displacement vector of bony structures was 1.84 mm.
  • Median displacement vector length of the prostate relative to bony structures was 1.9 mm.

Takeaway

During prostate cancer treatment, the prostate moves a little, but not too much, which helps doctors aim the radiation better.

Methodology

39 IMRT fractions in 5 prostate cancer patients were evaluated using pre- and post-treatment CBCT imaging.

Limitations

The study did not assess spurious, reversible movements of the prostate during beam-on-time.

Participant Demographics

5 patients with intermediate risk prostate cancer.

Digital Object Identifier (DOI)

10.1186/1748-717X-3-37

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