Associations of Muscle‐Related Metrics With Respiratory Disease in Chinese Adults: A Prospective Cohort Study
2025

Muscle Metrics and Respiratory Disease in Chinese Adults

Sample size: 17510 publication 10 minutes Evidence: moderate

Author Information

Author(s): Lan Yongbing, Ke Yalei, Sun Dianjianyi, Pei Pei, Yang Ling, Chen Yiping, Du Huaidong, Lv Silu, Barnard Maxim, Chen Junshi, Chen Zhengming, Lv Jun, Li Liming, Yu Canqing

Primary Institution: Peking University

Hypothesis

The study aims to examine the associations of muscle mass, strength, and quality with respiratory disease in Chinese adults.

Conclusion

Low grip strength and arm muscle quality are associated with increased risks of respiratory disease in Chinese adults.

Supporting Evidence

  • Low grip strength was associated with a 31% increased risk of respiratory disease.
  • Low arm muscle quality was associated with a 25% increased risk of respiratory disease.
  • Each standard deviation decrease in grip strength was linked to a 22% increased risk of respiratory disease.
  • Each standard deviation decrease in arm muscle quality was linked to a 14% increased risk of respiratory disease.

Takeaway

If you have weak muscles, you might be more likely to get sick with breathing problems. It's important to keep your muscles strong!

Methodology

A prospective cohort study using data from the China Kadoorie Biobank, analyzing muscle metrics and respiratory disease incidence.

Potential Biases

Self-reported data may introduce measurement errors.

Limitations

The study relied on self-reported data and had a relatively short follow-up period.

Participant Demographics

Participants aged 38-88, 65.4% women, with a mean age of 57.8 years.

Statistical Information

P-Value

p=0.137 for grip strength and p=0.102 for arm muscle quality.

Confidence Interval

1.31 (1.14–1.51) for low grip strength and 1.25 (1.09–1.44) for low arm muscle quality.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/jcsm.13650

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