Experimental Models in Penile Transplantation: Translational Insights and Relevance to Clinical Application
2024

Insights into Penile Transplantation Models

publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Kodali Naga Anvesh, Janarthanan Ramu, Sazoglu Bedreddin, Demir Zeynep, Dirican Omer Faruk, Kulahci Yalcin, Zor Fatih, Gorantla Vijay S

Primary Institution: Wake Forest School of Medicine

Hypothesis

This review aims to assess the contemporary literature on animal models for penile transplantation and their relevance to clinical applications.

Conclusion

The study highlights the need for better animal models to improve clinical outcomes in penile transplantation.

Supporting Evidence

  • Five cases of penile transplantation have been performed worldwide.
  • Animal models are essential for understanding the feasibility and outcomes of penile transplantation.
  • Current models do not fully address the clinical challenges faced in penile transplantation.

Takeaway

This study looks at how scientists use animals to learn about penis transplants, which can help doctors do better surgeries in the future.

Methodology

The authors conducted a comprehensive PubMed search from January 2000 to October 2023, focusing on animal models for penile transplantation.

Limitations

Current animal models do not fully replicate the clinical challenges of penile transplantation.

Digital Object Identifier (DOI)

10.7759/cureus.74258

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