Milk allergy and bottles over the back fence: two single patient trials
2008
Milk Allergy in Two Children: A Case Report
Sample size: 2
publication
Evidence: low
Author Information
Author(s): Bruce Arroll, Harry Pert, Gordon Guyatt
Primary Institution: University of Auckland, New Zealand
Hypothesis
Is allergy to cow's milk responsible for symptoms in two children?
Conclusion
A systematic approach enabled conclusive diagnoses in both children.
Supporting Evidence
- One child showed a clear relationship between cow's milk and symptoms.
- The other child showed no relationship with the type of milk consumed.
- Parents were relieved by the outcomes of the trials.
Takeaway
This study looked at two babies to see if cow's milk was making them sick. One baby had an allergy, and the other did not.
Methodology
Single patient trial with alternating bottles of soya-based milk and cow's milk.
Potential Biases
Parents were not blinded to the type of milk but had no incentive to cheat.
Limitations
No specific diagnostic tests were conducted and no other interventions were tried.
Participant Demographics
Two children aged about 6 months with no significant medical history.
Digital Object Identifier (DOI)
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