Gender differences in lung cancer risk by smoking: a multicentre case–control study in Germany and Italy
2000

Gender Differences in Lung Cancer Risk by Smoking

Sample size: 5722 publication Evidence: moderate

Author Information

Author(s): Kreuzer M, Boffetta P, Whitley E, Ahrens W, Gaborieau V, Heinrich J, Jöckel K H, Kreienbrock L, Mallone S, Merletti F, Roesch F, Zambon P, Simonato L

Primary Institution: GSF – Institute of Epidemiology

Hypothesis

Is there a difference in lung cancer risk between men and women based on smoking habits?

Conclusion

For comparable exposure to tobacco smoke, the risk of lung cancer is similar in women and men.

Supporting Evidence

  • Lung cancer risk was higher among men than women when comparing ever-smokers to never-smokers.
  • After adjusting for smoking variables, risk estimates were similar for both genders.
  • The study included a large sample size of over 5700 participants.

Takeaway

This study looked at how smoking affects lung cancer risk in men and women. It found that when men and women smoke the same amount, they have similar risks of getting lung cancer.

Methodology

A case–control study with personal interviews and standardized questionnaires to gather smoking and occupational histories.

Participant Demographics

3723 male and 900 female lung cancer cases, and 4075 male and 1094 female controls.

Statistical Information

Confidence Interval

95% CI 12.8–20.3 for men, 95% CI 3.5–5.1 for women

Digital Object Identifier (DOI)

10.1054/bjoc.1999.0904

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