Competitive Exclusion of Salmonella Enteritidis by Salmonella Gallinarum in Poultry
2000

How Salmonella Enteritidis Replaced Salmonella Gallinarum in Poultry

publication Evidence: moderate

Author Information

Author(s): Wolfgang Rabsch, Billy M. Hargis, Renee M. Tsolis, Robert A. Kingsley, Karl-Heinz Hinz, Helmut Tschape, Andreas J. Baumler

Primary Institution: Texas A&M University

Hypothesis

Salmonella Enteritidis filled the ecologic niche vacated by eradication of Salmonella Gallinarum from domestic fowl.

Conclusion

The eradication of Salmonella Gallinarum from poultry flocks contributed to the rise of Salmonella Enteritidis as a major foodborne pathogen.

Supporting Evidence

  • Salmonella Enteritidis emerged as a major egg-associated pathogen in the late 20th century.
  • The number of human S. Enteritidis cases is inversely related to the prevalence of S. Gallinarum in poultry.
  • Mathematical models suggest that S. Gallinarum competitively excluded S. Enteritidis from poultry flocks early in the 20th century.

Takeaway

When one type of Salmonella was removed from chickens, another type took its place and started making people sick.

Methodology

Retrospective analysis of epidemiologic surveys in Germany and mathematical modeling combining epidemiology with population biology.

Limitations

The estimates of the basic case-reproductive number for Salmonella Enteritidis are based on data from the late 1980s and may not reflect earlier conditions.

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