The Colon Health and Life-Long Exercise Change trial: a randomized trial of the National Cancer Institute of Canada Clinical Trials Group
2008

The Colon Health and Life-Long Exercise Change Trial

Sample size: 962 publication Evidence: moderate

Author Information

Author(s): Kerry S. Courneya, C.M. Booth, S. Gill, P. O’Brien, J. Vardy, C.M. Friedenreich, H.J. Au, M.D. Brundage, D. Tu, H. Dhillon, R.M. Meyer

Primary Institution: University of Alberta

Hypothesis

Colon cancer survivors randomized to the physical activity intervention arm will experience improvements in disease-free survival, patient-reported outcomes, and objective physical functioning as compared with survivors allocated to general health education.

Conclusion

The study aims to determine if a structured physical activity intervention can improve disease outcomes in colon cancer survivors.

Supporting Evidence

  • Observational studies suggest that physical activity is associated with improved disease outcomes in colon cancer survivors.
  • The study will evaluate the effects of a structured physical activity intervention over three years.
  • Previous research indicates that higher levels of physical activity correlate with better disease-free survival rates.

Takeaway

This study is trying to find out if exercising can help people who have had colon cancer feel better and live longer.

Methodology

Participants will be randomly assigned to either a structured physical activity intervention or general health education materials, with evaluations of disease-free survival and other health outcomes over three years.

Limitations

The study may face challenges in participant adherence to the physical activity program.

Participant Demographics

Participants are medically-fit survivors of high-risk stage II or III colon cancer who have completed adjuvant chemotherapy within the last 2-6 months.

Statistical Information

Confidence Interval

0.39 to 0.85

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