A novel synthetic quantification standard including virus and internal report targets: application for the detection and quantification of emerging begomoviruses on tomato
2011

Detection and Quantification of Begomoviruses in Tomato Plants

Sample size: 32 publication 10 minutes Evidence: high

Author Information

Author(s): Péréfarres Frédéric, Hoareau Murielle, Chiroleu Frédéric, Reynaud Bernard, Dintinger Jacques, Lett Jean-Michel

Primary Institution: CIRAD, UMR PVBMT CIRAD-Université de la Réunion

Hypothesis

Can a novel synthetic quantification standard improve the detection and quantification of emerging begomoviruses in tomato plants?

Conclusion

Five duplex real-time PCR assays were developed to effectively detect and quantify a wide range of begomoviruses, which could aid in breeding programs and epidemiological surveys.

Supporting Evidence

  • Real-time PCRs were optimized for accurate detection and quantification over a range of viral DNA copies.
  • Different patterns of viral accumulation were observed between bipartite and monopartite begomoviruses.
  • PYMV accumulated more viral DNA than the monopartite viruses at each time point.

Takeaway

Scientists created a new test to find and measure viruses that make tomatoes sick, helping farmers know when to act.

Methodology

Five duplex real-time PCR assays were developed and optimized for detecting and quantifying viral DNA in artificially inoculated tomato plants.

Potential Biases

Potential biases in sampling and DNA extraction processes were minimized using an internal control.

Limitations

The study was limited to artificially inoculated plants and may not fully represent natural infections.

Participant Demographics

Tomato plants were used for the experiments, specifically cv. Farmer.

Statistical Information

P-Value

p<10-8

Confidence Interval

95%

Statistical Significance

p<10-8

Digital Object Identifier (DOI)

10.1186/1743-422X-8-389

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