Survival of Burkholderia pseudomallei in Water
2008
Survival of Burkholderia pseudomallei in Water
publication
Evidence: moderate
Author Information
Author(s): Richard A. Moore, Apichai Tuanyok, Donald E. Woods
Primary Institution: University of Calgary
Hypothesis
What physiological adaptations allow Burkholderia pseudomallei to survive in water?
Conclusion
B. pseudomallei survival in water requires an intact LPS core region.
Supporting Evidence
- B. pseudomallei can survive in water for at least 90 days.
- An intact LPS core is necessary for prolonged survival in water.
- Mutants lacking capsule and LPS oligosaccharide were not affected in their ability to survive in water.
Takeaway
This study found that a bacteria called B. pseudomallei can live in water for a long time, and it needs a special part of its outer layer to do so.
Methodology
Microarray analyses were performed on B. pseudomallei cultures transferred from Luria broth to distilled water, and various mutants were tested for survival in water.
Limitations
The study did not explore all possible factors affecting survival in water.
Digital Object Identifier (DOI)
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