Prostate cancer risk and consumption of fish oils: a dietary biomarker-based case–control study
1999

Prostate Cancer Risk and Fish Oils

Sample size: 797 publication Evidence: moderate

Author Information

Author(s): Norrish A E, Skeaff C M, Arribas G L B, Sharpe S J, Jackson R T

Primary Institution: University of Auckland

Hypothesis

Does the intake of fish oils reduce the risk of prostate cancer?

Conclusion

Higher levels of EPA and DHA in erythrocytes are associated with a reduced risk of prostate cancer.

Supporting Evidence

  • Reduced prostate cancer risk was associated with high erythrocyte phosphatidylcholine levels of EPA.
  • Reduced prostate cancer risk was associated with high erythrocyte phosphatidylcholine levels of DHA.
  • These findings support previous experimental studies suggesting dietary fish oils may lower prostate cancer risk.

Takeaway

Eating fish oils might help lower the chances of getting prostate cancer.

Methodology

Population-based case–control study examining erythrocyte biomarkers of EPA and DHA.

Participant Demographics

317 prostate cancer cases and 480 age-matched community controls from Auckland, New Zealand.

Statistical Information

Confidence Interval

0.37–0.95 for EPA; 0.39–0.98 for DHA

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6690835

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