Early oncological outcomes of delayed radical prostatectomy: A prospective, international, follow‐up analysis of the COVIDSurg‐Cancer study
2024

Outcomes of Delayed Radical Prostatectomy During COVID-19

Sample size: 476 publication 10 minutes Evidence: moderate

Author Information

Author(s): Arjun Nathan, Chuanyu Gao, Alexander Light, Cameron Alexander, Vinson Chan, Kevin Gallagher, Sinan Khadhouri, Michael Ng, Grant D. Stewart, Veeru Kasivisvanathan

Primary Institution: University College London

Hypothesis

Does delaying radical prostatectomy for more than 90 days affect oncological outcomes compared to scheduled surgery?

Conclusion

Delaying radical prostatectomy does not adversely impact early oncological outcomes across all risk groups.

Supporting Evidence

  • High-risk men were prioritized for surgery during the COVID-19 pandemic.
  • Delaying surgery did not increase the rate of positive surgical margins.
  • Upstaging was more common in the delayed surgery group, but this did not affect overall outcomes.

Takeaway

This study found that waiting longer than 90 days for prostate cancer surgery doesn't seem to harm patients, and it might even help them think about their treatment options more.

Methodology

Patients with prostate cancer scheduled for surgery were followed for 1 year, comparing outcomes between those who had surgery within 90 days and those who had surgery after 90 days.

Potential Biases

There may be selection bias due to the prioritization of high-risk patients for surgery.

Limitations

The study is limited by a short follow-up period, which restricts long-term conclusions.

Participant Demographics

The study included men with localized prostate cancer, with a mix of high-risk and intermediate-risk patients.

Statistical Information

P-Value

0.512

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/bco2.433

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