Cognitive Function and Disability in Schizophrenia Patients in Remission
Author Information
Author(s): Krishnadas Rajeev, Moore Brian P, Nayak Ajita, Patel Ramesh R
Primary Institution: BYL Nair Hospital, Mumbai, India
Hypothesis
Is there a relationship between cognitive function and functional disability in patients with schizophrenia in remission compared to normal controls?
Conclusion
Patients with schizophrenia in remission show persistent cognitive deficits that are not associated with their functional disability.
Supporting Evidence
- Patients with schizophrenia showed significant deficits in attention, memory, and executive function compared to normal controls.
- No significant relationship was found between cognitive function and disability scores.
- The study highlights the role of socio-cultural factors in improving functional outcomes for patients.
Takeaway
People with schizophrenia can still have trouble thinking clearly even when they feel better, but having a job and family support can help them live better lives.
Methodology
The study compared cognitive function in 25 patients with schizophrenia in remission to 25 normal controls using various cognitive tests.
Potential Biases
The investigator was not blind to the diagnosis, which could introduce bias.
Limitations
The small sample size and potential observer bias may affect the results.
Participant Demographics
Patients aged 18–60 years, with a diagnosis of schizophrenia in remission.
Statistical Information
P-Value
<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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