Influence of an enhanced recovery programme on clinical outcomes and health-related quality of life after pancreaticoduodenectomy ad modum Whipple – an explorative and comparative single-centre study
2024

Impact of Enhanced Recovery Program on Outcomes After Pancreatic Surgery

Sample size: 138 publication Evidence: moderate

Author Information

Author(s): Andersson Thomas, Engström My, Wennerblom Johanna, Gyllensten Hanna, Bjerså Kristofer

Primary Institution: University of Gothenburg

Hypothesis

How does an enhanced recovery program affect clinical outcomes and health-related quality of life after pancreaticoduodenectomy?

Conclusion

The study found no significant differences in health-related quality of life between patients who participated in an enhanced recovery program and those who did not, but a significant decrease in length of stay was observed with the program.

Supporting Evidence

  • The ERP cohort had a significantly shorter length of stay compared to the pre-ERP cohort.
  • Health-related quality of life scores were similar between the two cohorts at baseline and follow-up.
  • Patients in the ERP cohort reported higher scores in some health measures at six months.

Takeaway

This study looked at how a special recovery program helps people after pancreatic surgery. It found that while the program didn't change how patients felt about their health, it did help them leave the hospital faster.

Methodology

This was an explorative and comparative single-centre study comparing a prospective cohort receiving an enhanced recovery program with a retrospective pre-program cohort.

Potential Biases

The retrospective data collection in the pre-ERP cohort may have introduced selection bias.

Limitations

The study had a small sample size and was conducted at a single center, which may limit the generalizability of the findings.

Participant Demographics

The study included 73 patients in the ERP cohort and 65 in the pre-ERP cohort, with a higher proportion of comorbidities in the ERP group.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/s12893-024-02667-x

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