Vitamin C in plasma is inversely related to blood pressure and change in blood pressure during the previous year in young Black and White women
2008

Vitamin C and Blood Pressure in Young Women

Sample size: 242 publication Evidence: moderate

Author Information

Author(s): Gladys Block, Christopher D. Jensen, Edward P. Norkus, Mark Hudes, Patricia B. Crawford

Primary Institution: University of California, Berkeley

Hypothesis

Plasma ascorbic acid concentration at the 10th annual follow-up visit would be inversely associated with blood pressure.

Conclusion

Plasma ascorbic acid was found to be inversely associated with blood pressure and change in blood pressure during the prior year.

Supporting Evidence

  • Higher plasma ascorbic acid levels were associated with lower systolic and diastolic blood pressure.
  • Participants in the highest quartile of plasma ascorbic acid had significantly lower blood pressure compared to those in the lowest quartile.
  • The study suggests that vitamin C may influence blood pressure regulation in healthy young adults.

Takeaway

This study found that higher levels of vitamin C in the blood are linked to lower blood pressure in young women.

Methodology

The study involved 242 Black and White women aged 18–21 years, measuring plasma ascorbic acid and blood pressure at the 10th annual follow-up of a longitudinal study.

Potential Biases

Dietary variables may be correlated with lifestyle variables, potentially confounding the results.

Limitations

The study is cross-sectional, so causality cannot be inferred.

Participant Demographics

Participants were young-adult women aged 18–21, consisting of 155 Blacks and 87 Whites.

Statistical Information

P-Value

0.005

Confidence Interval

95% CI 1.10 to 8.22 mmHg for systolic BP; 95% CI 2.70 to 9.38 mmHg for diastolic BP

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1475-2891-7-35

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