Assessment of blood flow patterns in the pulmonary artery using 4D flow
2011

Blood Flow Patterns in the Pulmonary Artery

Sample size: 20 publication Evidence: moderate

Author Information

Author(s): Bächler Pablo, Pinochet Natalia, Tejos Cristián, Gerard Crelier, Irrarázabal Pablo, Uribe Sergio

Primary Institution: Pontificia Universidad Católica de Chile

Hypothesis

To perform hemodynamic analysis in the pulmonary artery in volunteers and patients with congenital heart disease after Glenn procedure.

Conclusion

Vortices are normally found in the pulmonary artery in healthy subjects, but abnormal blood flow patterns are seen in patients after the Glenn procedure.

Supporting Evidence

  • Two vortices were identified in the pulmonary artery in volunteers.
  • VO1 was seen in all volunteers and VO2 in sixteen.
  • VO1 was smaller compared to VO2, occupying 24% of vessel area versus 31%.
  • VO1’s center was closer to the vessel’s center compared to VO2’s center.
  • Abnormal vortices were detected in both patients after the Glenn procedure.

Takeaway

Doctors studied how blood flows in the lungs of healthy people and patients who had heart surgery. They found that healthy people have normal flow patterns, while patients have unusual ones.

Methodology

Eighteen volunteers and two patients underwent 4D Flow scans, and flow patterns were analyzed using specific software and planes.

Participant Demographics

Eighteen volunteers and two patients with congenital heart disease.

Statistical Information

P-Value

0.03

Statistical Significance

p=0.03

Digital Object Identifier (DOI)

10.1186/1532-429X-13-S1-P66

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