Aspirin and risk for gastric cancer: a population-based case–control study in Sweden
2001
Aspirin and Gastric Cancer Risk
Sample size: 1732
publication
Evidence: moderate
Author Information
Author(s): Akre K, Ekström A M, Signorello L B, Hansson L-E, Nyrén O
Primary Institution: Karolinska Institutet
Hypothesis
Does aspirin use reduce the risk of gastric cancer?
Conclusion
Aspirin users have a moderately reduced risk of gastric cancer compared to non-users.
Supporting Evidence
- Users of aspirin had an odds ratio of 0.7 for gastric cancer risk.
- The risk reduction was consistent for both cardia and non-cardia tumors.
- No clear association was found between gastric cancer risk and non-aspirin NSAIDs.
Takeaway
Taking aspirin might help lower the chances of getting stomach cancer.
Methodology
The study involved interviews with 567 gastric cancer cases and 1165 controls about their pain reliever use.
Participant Demographics
Participants included individuals from 5 Swedish counties, with cases classified by subsite and histological type.
Statistical Information
P-Value
0.02
Confidence Interval
0.6–1.0
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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