Cricket Chitosan for Nanoparticle Development
Author Information
Author(s): Inthorn Jirasit, Chomchalao Pratthana, Rithchumpon Puracheth, Juntrapirom Saranya, Kanjanakawinkul Watchara, Rades Thomas, Chaiyana Wantida
Primary Institution: Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University
Hypothesis
This study aimed to assess the potential of cricket-derived chitosan as a natural source to develop chitosan nanoparticles (CNPs).
Conclusion
Cricket-derived chitosan compares favorably with crustacean-derived chitosan and shows potential for use in nanocosmeceutical delivery systems.
Supporting Evidence
- Chitosan can be successfully isolated from three cricket species.
- Cricket-based chitosan displayed higher crystallinity and lower molecular weight compared to commercial chitosan.
- Chitosan derived from A. domesticus produced the smallest particle size and acceptable zeta potential.
- All cricket-based chitosan exhibited no irritation or cytotoxicity.
Takeaway
Scientists found that chitosan from crickets can be used to make tiny particles for skin care products, which could be better than those made from shrimp.
Methodology
Chitosan was isolated from different cricket species and characterized for various properties; nanoparticles were developed using an ionotropic gelation method.
Limitations
The study did not explore the long-term stability of the nanoparticles in various formulations.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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