Cost Effectiveness and Resource Allocation
2008

Cost-Effectiveness of Smoking Cessation to Prevent Age-Related Macular Degeneration

Sample size: 1488 publication 10 minutes Evidence: high

Author Information

Author(s): Susan F. Hurley, Jane P. Matthews, Robyn H. Guymer

Primary Institution: Bainbridge Consultants

Hypothesis

Does smoking cessation reduce the risk of age-related macular degeneration and is it cost-effective?

Conclusion

Smoking cessation is unequivocally cost-effective in terms of its impact on age-related macular degeneration outcomes alone.

Supporting Evidence

  • Quitting smoking can lead to 48 fewer cases of macular degeneration for every 1,000 smokers who quit.
  • Smoking cessation was cost-saving when caregiver costs were included in the analysis.
  • The cost per QALY gained through quitting smoking was only $197 when caregiver costs were excluded.

Takeaway

If people stop smoking, they can lower their chances of getting eye problems as they get older, and it can save money too.

Methodology

A Markov model was developed to simulate the risk and progression of macular degeneration in smokers and quitters, using data from 7 studies involving 1,488 patients.

Limitations

The analysis focused solely on macular degeneration and did not consider other health benefits of quitting smoking.

Participant Demographics

The study involved a hypothetical cohort of 1,000 smokers, stratified by age and sex, representing the U.S. population of smokers in 2004.

Statistical Information

Confidence Interval

90 – 241

Digital Object Identifier (DOI)

10.1186/1478-7547-6-18

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