Tophaceous Gout and Renal Insufficiency: A New Solution for an Old Therapeutic Dilemma
2011

New Treatment for Gout in Elderly with Kidney Issues

Sample size: 1 publication Evidence: low

Author Information

Author(s): Anne-Kathrin Tausche, Carsten Wunderlich, Martin Aringer

Primary Institution: University Clinic “Carl Gustav Carus” of the Technical University of Dresden

Conclusion

The treatment with febuxostat successfully controlled serum uric acid levels, stopped gout attacks, and resolved tophi in the patient.

Supporting Evidence

  • The patient had recurrent gouty arthritis for 4 years with high serum uric acid levels.
  • Allopurinol was ineffective due to intolerance, and benzbromarone was ineffective due to renal impairment.
  • Febuxostat treatment led to a rapid decrease in serum urate levels.

Takeaway

An 87-year-old woman with severe gout and kidney problems was treated with a new medicine called febuxostat, which helped her feel better and reduced her gout symptoms.

Methodology

The patient was treated with febuxostat and monitored for changes in serum uric acid levels and gout symptoms.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

An 87-year-old woman with chronic tophaceous gout and renal insufficiency.

Digital Object Identifier (DOI)

10.1155/2011/397646

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