HIV-1 Prevalence in Northern Uganda
Author Information
Author(s): Fabiani Massimo, Nattabi Barbara, Pierotti Chiara, Ciantia Filippo, Opio Alex A, Musinguzi Joshua, Ayella Emintone O, Declich Silvia
Primary Institution: National Centre for Epidemiology, Surveillance and Health Promotion, Istituto Superiore di Sanità, Rome, Italy
Hypothesis
What is the HIV-1 prevalence among pregnant women in conflict-affected northern Uganda and what factors are associated with infection?
Conclusion
HIV-1 prevalence in northern Uganda remains high, particularly among women living outside of protected camps.
Supporting Evidence
- The overall HIV-1 prevalence in the Acholi region was estimated at 8.2%.
- Internally displaced women had a lower risk of HIV-1 infection compared to those living outside of protected camps.
- Older age groups showed higher adjusted odds ratios for HIV-1 infection.
Takeaway
This study looked at how many pregnant women in northern Uganda have HIV and found that those living in camps are less likely to be infected than those living outside.
Methodology
3051 antenatal clinic attendees were anonymously tested for HIV-1 infection and factors associated with infection were evaluated using logistic regression models.
Potential Biases
Possible differences in ANC attendance between HIV-positive and HIV-negative women could affect representativeness.
Limitations
The study may not fully represent the entire population due to the focus on specific ANC sites and potential biases in attendance.
Participant Demographics
Participants were pregnant women attending antenatal clinics in Gulu, Kitgum, and Pader districts, with a significant proportion being internally displaced.
Statistical Information
P-Value
0.002
Confidence Interval
95% CI: 1.15–2.08
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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