Hepatitis B Virus Genotypes in Afghanistan
Author Information
Author(s): Attaullah Sobia, Rehman Saif ur, Khan Sanaullah, Ali Ijaz, Ali Sajid, Khan Shahid Niaz
Primary Institution: Kohat University of Science and Technology
Hypothesis
What are the prevalent HBV genotypes in HBsAg positive individuals in Afghanistan?
Conclusion
The study found a heterogeneous distribution of HBV genotypes in Afghanistan, with genotype D being the most common.
Supporting Evidence
- Genotype D was found in 35.67% of the patients.
- Genotype C was observed in 32.16% of the patients.
- Genotype A was found in 19.30% of the patients.
- Genotype B was present in 7.02% of the patients.
- 6.07% of individuals were not typed.
Takeaway
This study looked at people in Afghanistan who have hepatitis B and found different types of the virus, with one type being the most common.
Methodology
The study included 214 HBsAg-positive patients, confirmed HBV DNA with nested PCR, and performed type-specific PCR for HBV genotyping.
Potential Biases
Potential bias due to the lack of patient identification and consent.
Limitations
The study did not take written consent from patients and did not identify patients by name or number.
Participant Demographics
168 males and 46 females, aged 18 to 71 years.
Digital Object Identifier (DOI)
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