Pancreaticojejunostomy for Severe Symptomatic Chronic Pancreatitis
1992

Pancreaticojejunostomy for Chronic Pancreatitis

Sample size: 13 publication Evidence: moderate

Author Information

Author(s): G.W.L. Denton, W.A. Brough, D.E.F. Tweedle

Primary Institution: University Hospital of South Manchester

Hypothesis

Can pancreaticojejunostomy relieve pain and prevent pancreatic organ failure in patients with chronic pancreatitis?

Conclusion

Pancreaticojejunostomy can relieve pain in patients with chronic pancreatitis, but it is less effective in preventing pancreatic exocrine failure.

Supporting Evidence

  • Pain relief was achieved in nine out of twelve surviving patients.
  • Exocrine function deteriorated in four patients post-surgery.
  • Endocrine function remained unchanged in ten out of twelve patients.

Takeaway

Doctors did surgery to help people with bad stomach pain from a pancreas problem, and it worked for most of them, but not all.

Methodology

The study involved 13 patients who underwent pancreaticojejunostomy, selected from 211 patients referred for chronic pancreatitis over six years.

Limitations

The follow-up period was relatively short, and the long-term effects on pancreatic function remain uncertain.

Participant Demographics

Nine males and four females with a median age of 42 years.

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication