Skin Tear Treatment with Copaifera multijuga Hayne in Polymeric Hydrogel: A Randomized Clinical Trial
2024

Copaifera multijuga for Skin Tear Treatment

Sample size: 84 publication 10 minutes Evidence: moderate

Author Information

Author(s): Cardinelli Camila Castanho, Passos Jéssica Teixeira Gâmba, Veiga-Junior Valdir Florêncio, de Oliveira Beatriz Guitton Renaud Baptista, dos Santos Elisabete Pereira, Neto Guilherme Guilhermino, Di Piero Karina Chamma, de Freitas Zaida Maria Faria

Primary Institution: Federal University of Rio de Janeiro

Hypothesis

Does the addition of Copaifera multijuga Hayne oleoresin to a hydrogel improve skin tear healing compared to standard treatment?

Conclusion

CopaibaPolyHy-2 is effective, offering faster healing times and better tissue quality for skin tears compared to CopaibaPolyHy-10.

Supporting Evidence

  • 100% of wounds healed by the end of the study.
  • CopaibaPolyHy-2 showed significantly faster healing than CopaibaPolyHy-10.
  • Participants experienced no serious adverse effects during the study.
  • Weekly follow-ups monitored the healing progress of participants.

Takeaway

This study tested a special gel with copaiba oil to help heal skin tears faster. It worked better than a stronger version of the gel.

Methodology

A double-blind, randomized, controlled clinical trial was conducted with 84 patients to compare healing times of skin tears treated with different concentrations of Copaifera oleoresin in hydrogel.

Potential Biases

Potential bias due to the exclusion of participants who did not complete the treatment.

Limitations

The study had a loss of follow-up for some participants, and the effects of systemic factors on healing were not fully explored.

Participant Demographics

Predominantly male participants with a mean age of 67.37 years, including common underlying diseases like hypertension and diabetes.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/ph17121691

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