Incidence of Dual AV Node Physiology Following Termination of AV Nodal Reentrant Tachycardia by Adenosine-5'-Triphosphate: A Comparison with Drug Administration in Sinus Rhythm
2003

Dual AV Node Physiology After AV Nodal Reentrant Tachycardia Treatment

Sample size: 82 publication Evidence: moderate

Author Information

Author(s): Belhassen Bernard MD, Fish Roman MD, Viskin Sami MD, Glick Aharon MD, Glikson Michael MD, Eldar Michael MD

Primary Institution: Tel-Aviv Sourasky Medical Center

Hypothesis

What is the incidence of dual AV node physiology following termination of AV nodal reentrant tachycardia with adenosine triphosphate compared to drug administration in sinus rhythm?

Conclusion

Dual AV node physiology is present in a significant proportion of patients following the termination of AV nodal reentrant tachycardia with adenosine triphosphate.

Supporting Evidence

  • 75.6% of patients with AVNRT showed signs of dual AV node physiology after ATP administration in sinus rhythm.
  • 36.5% of patients exhibited dual AV node physiology after termination of AVNRT with ATP.
  • None of the control patients with AVRT showed dual AV node physiology during ATP testing.

Takeaway

When doctors use a special medicine called ATP to stop a fast heartbeat, many patients show signs of a second way their heart can beat, which helps doctors understand what's happening.

Methodology

The study involved administering incremental doses of ATP to patients with AVNRT and observing the occurrence of dual AV node physiology and AV block.

Limitations

Results cannot be extrapolated to clinical settings as the study was conducted during controlled electrophysiologic procedures.

Participant Demographics

The study included 82 patients (53 females, 29 males) with an average age of 46 years.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

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