A double-blind, randomized, multicentric, placebo-controlled clinical trial of antarth, a phytomedicine, in the treatment of osteoarthritis
2011

Efficacy of Antarth in Treating Osteoarthritis

Sample size: 90 publication 10 minutes Evidence: moderate

Author Information

Author(s): Anil K. Gupta, Kirankumar Acharya, Parag S. Sancheti, Ramchandra S. Joshi

Primary Institution: G.S.V.M. Medical College, Kanpur

Hypothesis

To test Antarth, a polyherbal phytomedicine, for its efficacy and safety in patients with osteoarthritis compared to placebo.

Conclusion

Patients treated with Antarth reported greater satisfaction and reduced pain compared to those on placebo.

Supporting Evidence

  • Patients treated with Antarth reported a significant reduction in pain during daily activities compared to placebo.
  • 100% of patients in the Antarth group were satisfied with their treatment.
  • Antarth group showed a greater reduction in the need for rescue medication compared to placebo.

Takeaway

This study tested a herbal medicine called Antarth for knee pain from arthritis, and it helped people feel better than a fake pill.

Methodology

90 patients with osteoarthritis were randomly assigned to receive either Antarth or placebo for 3 months, with assessments every month.

Potential Biases

Potential bias from the subjective nature of patient assessments.

Limitations

The study had a dropout of 2 patients and may not be generalizable due to specific inclusion criteria.

Participant Demographics

44 males and 44 females, mean age 52.7 years.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4103/0253-7613.75674

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