Highly Pathogenic Avian Influenza Virus (H5N1) in Domestic Poultry and Relationship with Migratory Birds, South Korea
2008

H5N1 Avian Influenza in Poultry and Migratory Birds in South Korea

Sample size: 6500 publication Evidence: moderate

Author Information

Author(s): Lee Youn-Jeong, Choi Young-Ki, Kim Yong-Joo, Song Min-Suk, Jeong Ok-Mi, Lee Eun-Kyoung, Jeon Woo-Jin, Jeong Wooseog, Joh Seong-Joon, Choi Kang-seuk, Her Moon, Kim Min-Chul, Kim Aeran, Kim Min-Jeong, ho Lee Eun, Oh Tak-Gue, Moon Ho-Jin, Yoo Dae-Won, Kim Jae-Hong, Sung Moon-Hee, Poo Haryoung, Kwon Jun-Hun, Kim Chul-Joong

Primary Institution: Ministry of Agriculture and Forestry, Anyang, South Korea

Hypothesis

Is there a relationship between H5N1 outbreaks in domestic poultry and migratory birds in South Korea?

Conclusion

The study found that H5N1 strains in domestic poultry were closely related to those isolated from migratory bird habitats.

Supporting Evidence

  • Phylogenetic analysis showed that all isolates were closely related.
  • Two distinct H5N1 strains were isolated from migratory bird habitats.
  • The mortality rate in the first outbreak was 86% among affected chickens.
  • Subsequent outbreaks had lower mortality rates due to early reporting and culling.
  • All 2006–2007 isolates were QH/05-like strains.
  • Environmental isolates were obtained after poultry outbreaks.

Takeaway

This study looked at sick chickens and wild birds to see if they were spreading a virus called H5N1 to each other.

Methodology

Virus strains were isolated from domestic poultry and migratory bird habitats, followed by phylogenetic analysis.

Limitations

The study cannot definitively conclude whether migratory birds were the source of the H5N1 virus in poultry or vice versa.

Participant Demographics

The study involved domestic poultry and migratory birds in South Korea.

Digital Object Identifier (DOI)

10.3201/eid1403.070767

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