Breast Cancer Biology: The Multifaceted Roles of Mesenchymal Stem Cells
2008
Breast Cancer Biology: The Multifaceted Roles of Mesenchymal Stem Cells
publication
Author Information
Author(s): Shyam A. Patel, Andew C. Heinrich, Bobby Y. Reddy, Balaji Srinivas, Nicole Heidaran, Pranela Rameshwar
Primary Institution: University of Medicine and Dentistry of New Jersey
Conclusion
The study highlights the complex interactions between breast cancer cells and the bone marrow microenvironment, suggesting potential new treatment avenues.
Supporting Evidence
- Breast cancer remains the most common cancer among women in the United States.
- Metastasis to bone can lead to serious complications like fractures and reduced quality of life.
- Chemotherapy often fails to target dormant breast cancer cells in the bone marrow.
Takeaway
Breast cancer cells can hide in the bone marrow, making them hard to treat, and special cells called mesenchymal stem cells help them do this.
Digital Object Identifier (DOI)
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