Factors Associated with Death or ICU Admission Due to H1N1 Infection
Author Information
Author(s): Payam Tabarsi, Ahmadreza Moradi, Majid Marjani, Parvaneh Baghaei, Seyed Mohammadreza Hashemian, Seyed Alireza Nadji, Atefeh Fakharian, Davood Mansouri, Mohammadreza Masjedi, Aliakbar Velayati
Primary Institution: Masih-Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Hypothesis
What factors are associated with mortality and ICU admissions in patients with 2009 H1N1 infection?
Conclusion
The study found that delayed antiviral treatment and opium inhalation were significant risk factors for ICU admission and mortality in H1N1 patients.
Supporting Evidence
- 20 out of 46 confirmed hospitalized patients with H1N1 were admitted to the ICU.
- 7 patients (15%) died during the study.
- Opium inhalation was significantly related to ICU admission (P = 0.01).
- Symptoms like productive cough, hemoptysis, and chest pain were linked to ICU admission.
Takeaway
This study looked at people who got really sick from the H1N1 flu and found that waiting too long to get medicine and using opium made it more likely they would end up in the hospital or die.
Methodology
A retrospective cross-sectional study was conducted among patients with confirmed H1N1, analyzing demographic, clinical, and laboratory data.
Potential Biases
The lack of a control group limits the ability to generalize the findings.
Limitations
The study was retrospective, had a small sample size, and was conducted in a single tertiary care center.
Participant Demographics
The mean age of patients was 36.9 years, with a male-to-female ratio of 1.3:1.
Statistical Information
P-Value
0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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