Comparative efficacy of two primary care interventions to assist withdrawal from long term benzodiazepine use: A protocol for a clustered, randomized clinical trial
2011

Comparing Two Methods to Help People Stop Using Benzodiazepines

Sample size: 495 publication Evidence: moderate

Author Information

Author(s): Vicens Caterina, Socias Isabel, Mateu Catalina, Leiva Alfonso, Bejarano Ferran, Sempere Ermengol, Basora Josep, Palop Vicente, Mengual Marta, Beltran Jose Luis, Aragonès Enric, Lera Guillem, Folch Silvia, Piñol Josep Lluís, Esteva Magdalena, Roca Miguel, Arenas Arturo, del Mar Sureda María, Campoamor Francisco, Fiol Francisca

Primary Institution: Balearic Health service-IbSalut, Mallorca, Spain

Hypothesis

Can two different interventions by general practitioners effectively assist patients in withdrawing from long-term benzodiazepine use compared to routine care?

Conclusion

The study aims to evaluate the effectiveness and safety of two interventions for benzodiazepine withdrawal, which may lead to better outcomes than routine care.

Supporting Evidence

  • Benzodiazepines are effective but long-term use can lead to dependence and adverse effects.
  • The study will compare two interventions against routine care to help patients stop using benzodiazepines.
  • The trial will involve 495 patients across three regions in Spain.

Takeaway

This study is trying to find out if two different ways of helping people stop taking a certain medicine are better than just doing nothing special.

Methodology

A three-arm cluster randomized controlled trial involving general practitioners and patients taking benzodiazepines for at least 6 months.

Potential Biases

GPs in the control group may be more motivated to help patients withdraw due to awareness of the study.

Limitations

Potential contamination bias if GPs from different study arms work in the same healthcare center and the Hawthorne effect may influence usual care.

Participant Demographics

Patients aged 18-80 years, taking benzodiazepines for at least 6 months.

Digital Object Identifier (DOI)

10.1186/1471-2296-12-23

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication