Novel H1N1 influenza infection in intensive care unit
2011

H1N1 Influenza Infection in ICU Patients

publication Evidence: moderate

Author Information

Author(s): Chacko J, Gagan B, Ashok E, Radha M, Hemanth H. V.

Primary Institution: Manipal Hospital, Bangalore, India

Hypothesis

2009 H1N1 infection tends to be more common in previously well, relatively younger patients.

Conclusion

Severe 2009 H1N1 infection can lead to significant respiratory failure and requires prolonged ventilatory support.

Supporting Evidence

  • 2009 H1N1 infection is more common in younger patients.
  • 64.1% of patients had underlying risk factors like obesity and diabetes.
  • Median duration of ventilator support was 10 days.

Takeaway

This study shows that younger people can get very sick from H1N1 flu and may need a lot of help to breathe.

Methodology

Case series of patients admitted to an ICU during the 2009 H1N1 pandemic.

Limitations

The study did not include systematic echocardiographic studies to assess cardiac dysfunction.

Participant Demographics

Median age of patients was 35 years, with 64.1% having underlying risk factors.

Statistical Information

Confidence Interval

IQR 28.2–42.8 for age; IQR 4–22 days for ventilator support duration.

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